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AAPS PharmSciTech - Volume 6 Themed Topic Issue

Process Analytical Technology
Editor: Ajaz Husain

Table of Contents

Quantitative Analysis of Film Coating in a Pan Coater Based on In-Line Sensor Measurements
José D. Pérez-Ramos, W. Paul Findlay, Garnet Peck, Kenneth R. Morris

An Overview of Electrical Tomographic Measurements in Pharmaceutical and Related Application Areas
Gary T. Bolton and Ken M. Primrose

Pellet Manufacturing by Extrusion-Spheronization Using Process Analytical Technology
Niklas Sandler, Jukka Rantanen, Jyrki Heinämäki, Meike Römer, Martti Marvola, and Jouko Yliruusi

The Effects of Physical Parameters on Laser-Induced Breakdown Spectroscopy Analysis of Intact Tablets
Jean-Francois Archambault, Anda Vintiloìu, and Elizabeth Kwong

Process Analytical Technology Case Study Part I: Feasibility Studies for Quantitative Near-Infrared Method Development
Robert P. Cogdill, Carl A. Anderson, Miriam Delgado-Lopez, David Molseed, Robert Chisholm, Raymond Bolton, Thorsten Herkert, Ali M. Afnán, and James K. Drennen, III

Process Analytical Technology Case Study: Part II. Development and Validation of Quantitative Near-Infrared Calibrations in Support of a Process Analytical Technology Application for Real-Time Release
Robert P. Cogdill, Carl A. Anderson, Miriam Delgado, Robert Chisholm, Raymond Bolton, Thorsten Herkert, Ali M. Afnan, and James K. Drennen, III

Process Analytical Technology Case Study, Part III: Calibration Monitoring and Transfer
Robert P. Cogdill, Carl A. Anderson, and James K. Drennen, III

Excipient Selection Can Significantly Affect Solid-State Phase Transformation in Formulation During Wet Granulation
Sari Airaksinen, Milja Karjalainen, Niina Kivikero, Sari Westermarck, Anna Shevchenko, Jukka Rantanen, and Jouko Yliruusi

Evaluation of Manometric Temperature Measurement, a Process Analytical Technology Tool for Freeze-Drying: Part I, Product Temperature Measurement
Xiaolin Tang, Steven L. Nail, and Michael J. Pikal

Modeling Weight Variability in a Pan Coating Process Using Monte Carlo Simulations
Preetanshu Pandey, Manoj Katakdaunde, and Richard Turton

Preparation and Characterization of Pluronic–Colloidal Silicon Dioxide Composite Particles as Liquid Crystal Precursor
Manish Maheshwari, Anant Paradkar, Shigeo Yamamura, Shivajirao Kadam

Evaluation of Manometric Temperature Measurement, a Process Analytical Technology Tool for Freeze-drying: Part II Measurement of Dry-layer Resistance
Xiaolin Charlie Tang, Steven L. Nail, Michael J. Pikal

Evaluation of Manometric Temperature Measurement (MTM), a Process Analytical Technology Tool in Freeze Drying, Part III: Heat and Mass Transfer Measurement
Xiaolin Charlie Tang, Steven L. Nail, Michael J. Pikal

Solventless Photocurable Film Coating: Evaluation of Drug Release, Mechanical Strength, and Photostability
Sagarika Bose and Robin H. Bogner

Lubrication Potential of Magnesium Stearate Studied on Instrumented Rotary Tablet Press
Sarsvatkumar Patel, Aditya Mohan Kaushal, and Arvind Kumar Bansal

Determination of Figures of Merit for Near-Infrared and Raman Spectrometry by Net Analyte Signal Analysis for a 4-Component Solid Dosage System
Steven M. Short, Robert P. Cogdill, and Carl A. Anderson



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